Professor Melanie Flint

University’s public lecture explores the link between stress and cancer

University of Brighton’s public lecture in December shares insights into how stress hormones impact cancer.

Stress and cancer: The hidden link

Wednesday 4 December 2024 at 6.30pm, University of Brighton, Huxley Lecture Theatre (300), Huxley Building, Lewes Road, Brighton, BN2 4GJ

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What is the hidden link between stress and cancer? The first inaugural lecture for this academic year at the University of Brighton aims to shed light on the impact of stress responses on the progression and treatment of the disease.

Join Professor Melanie Flint, Professor of Stress and Cancer Research and co-director of the Sussex Cancer Research Centre, on Wednesday 4 December when she explores how chronic stress impacts quality of life and its link to cancer.

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My Experience Studying Ecology and Conservation in the UK 

My experience as a second year Ecology and Conservation degree student at Brighton 

Why I chose to study Ecology and Conservation 

Ever since I can remember I have been intrigued by wildlife. Growing up I used to spend my time watching nature documentaries, alongside visiting zoos and natural history museums. I grew up in the Chilterns where I was lucky to be surrounded by an amazing natural landscape, which was also home to the extremely successful Red Kite reintroduction. All of this fed my intrigue, leading me to study Ecology and Conservation at the University of Brighton. 

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Left to right - Dr Duncan Gilbert, Professor Timothy Humphrey, Professor Melanie Flint, Dr Simon Mitchell

Groundbreaking new cancer research centre unites top researchers, cancer specialists and patients to fight cancer in Sussex 

  • New cancer research centre unites researchers across Brighton and Sussex Medical School, University of Brighton, University of Sussex and NHS to share research and resource
  • Patients being put at the heart of the centre’s vision
  • Centre will provide a ‘life-cycle’ of research – from work in the lab, to drug discovery, to clinical trials, to treatments.

A brand new pioneering centre dedicated to improving cancer treatment and patient outcomes has opened today in Sussex. The Sussex Cancer Research Centre (SCRC), draws on the world-class cancer research from experts at Brighton and Sussex Medical School (BSMS), University of Brighton, University of Sussex and in the NHS.  

The groundbreaking centre aims to provide an environment where researchers, clinicians and patients can share resources, insight, experience and expertise to improve cancer treatments and patient outcomes.

The team behind the centre say that the venture represents a once-in-a-lifetime opportunity to deliver significant improvements in care for cancer patients and drive further improvements in the life-chances of those diagnosed with cancer – putting people at the forefront of their research

The four co-founders of the centre are: Dr Simon Mitchell, Reader in Cancer Systems Biology at BSMS; Professor Melanie Flint, Professor of Stress and Cancer Research at the University of Brighton; Professor Timothy Humphrey, Professor of Translational Research and Genome Stability at the University of Sussex; and Clinical Oncologist Dr Duncan Gilbert of University Hospitals Sussex NHS Foundation Trust.

Dr Simon Mitchell said: “From day one, this will be a true collaboration. As a team, with a united vision to improve care for patients, we are greater than the sum of our parts. Cancer doesn’t recognise institutional boundaries, and to beat cancer we must cross those boundaries too.”  

Professor Timothy Humphrey said: “Almost everyone knows someone affected by cancer and we need their perspective to provide valuable input into our research direction. Our central goal is improved patient outcomes through supporting world-leading collaborative research.”

Professor Melanie Flint said: “We want to make sure Sussex is the best place in the country to do cancer research, so that the future leaders want to work here and stay here. The Sussex Cancer Research Centre will help attract, mentor, and support, ambitious cancer researchers for the benefit of cancer patients.”

By connecting researchers, patients and clinical partners it is hoped that resources, such as patient samples, will be more readily available. Research within similar areas will be more collaborative, such as the University of Brighton and BSMS work to study the effects of stress on patient’s psychology and on patient’s cells respectively. Resulting findings can then be used to identify potential drug targets to be investigated using the University of Sussex’s drug discovery pipelines. New treatments can then be trialled in collaboration with NHS colleagues and the BSMS Clinical Trials Unit.

Dr Duncan Gilbert, Clinical Oncologist at University Hospitals Sussex NHS Foundation Trust, said: “University Hospitals Sussex serves the second largest cancer patient population of any NHS organisation and has plans to move its cancer services to a new purpose-built cancer centre. This, we believe, will facilitate greater interactions with the Sussex Cancer Research Centre, including scientists, clinicians and patients. And, together with our NHS partners, will help our work to improve outcomes alongside prevention, early detection, and improving care and support for those with cancer across Sussex.”

Sussex Health and Care Integrated Care System brings together the universities, NHS in Sussex, local authorities and wider partners with an interest in health and care. It agreed its five year strategy Improving Lives Together which was published last year and which sets out the ambition for how partners will work together to improve health and care outcomes of the Sussex population now and for the future.

At the heart of the SCRC is the involvement of people living with cancer, encouraging them to participate in research through trials, providing input into grant applications, talking to students, and even shaping the research taking place. It is hoped that eventually, this could lead to more patients being able to enroll on clinical trials without leaving the area. 

Artist Markus Taylor was diagnosed with Chronic Lymphocytic Leukaemia in 2021 and is a public member of SCRC said: “I am really happy to be part of the new research centre because I know the team is very keen to listen to what people with cancer have to say. The centre is not just about cells, molecules, proteins, it’s not just about us being objects, clients, subjects, patients, it’s about real people living with real disease.

“I hope this centre will help to develop those conversations that are already happening between all those tied together by cancer; the people that have it, the scientists, doctors and consultants – sharing information, sharing knowledge and stories.  Let’s talk, let’s share things, let’s move things on. To be part of that is incredible.”

The centre will also benefit the next generation of cancer researchers by giving both undergraduate and postgraduate students at the three institutions the opportunity to get involved as part of their studies with mentoring programmes and a PhD studentship benefitting from the experience of working with a multi-institution and interdisciplinary cancer research centre.

Anybody wishing to know more should go to (www.sussexcancer.org) and click “Get Involved”. There will also be a chance to meet cancer researchers and learn more at events which will be announced through the website.  

ENDS

Introductory SCRC film

A full interview with Markus Taylor is enclosed as a separate file.

Educational initiatives offered by SCRC include:

Cancer mentoring program: Allowing experienced researchers to mentor more junior researchers across institutions to provide advice and training. 

Research grants: Four ‘pump priming’ grants worth £15,000 each donated by BSMS, University of Brighton, University of Sussex and the Sussex Cancer Fund will be used to build collaborations across multiple institutions with the SCRC. It is hoped that this will lead to larger multi-site grant submissions. 

PhD studentship: A three-year fully funded PhD studentship funded by BSMS and the School of Life Sciences at University of Sussex to encourage research excellence and solidify a new multi-institution collaboration.

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Making the leap to study in Brighton from Greece gave me tools for life

International Pharmacy alum Polyxeni Tsea tells us how her university experience as a whole, not just her degree, set her up for a successful career in the pharmaceutical industry.

As an international student coming to the UK, Polyxeni tells us how the University of Brighton equipped her both personally and professionally for life and career beyond graduation.

She tells us about learning independence in a new country, the experience of meeting people from all around the world working as a Student Residential Advisor and how her degree has directly linked to her career working for DEMO S.A.

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Scholarship provides a boost for University of Brighton student

Pharmacy student, Grace Oreyeni, was awarded the Black and Black-Mixed Heritage Progression Scholarship.

The Progression Scholarship includes financial support as well as access to other support, such as free gym membership and access to mentoring and networking opportunities. Here she tells us how the scholarship has impacted her so far.

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Science Saturday Club for students in Years 10 and 11 at the University of Brighton 

I have learnt many facts and experiments from various sciences as well as the process of applying to university and what it maybe like. I found the experiments enjoyable and the talks on university and post 16 options useful

Lucas

The university outreach team organised a Science Saturday Club, which ran over four Saturday mornings earlier in the year. 27, Sussex-based year 10 and 11 students from schools as far away as Littlehampton and Hastings attended the club held on Saturday mornings, which combined lectures and lab sessions run by academics and PhD students interspersed with information and guidance about post-16 options, a tour of our Moulsecoomb campus and plenty of opportunity to engage with three Applied Science student ambassadors supporting the club. The club, which was free to attend, aimed to show students what studying science at university is like.

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My course so far

Hi I’m Jade and I’m a first year studying Biological Sciences BSc(Hons) and here’s what I think of the course so far…

I chose this course as I’ve been interested in biology for many years, and I like that this course specifically allows you to cater it more specifically to yourself with how many option modules there are for later years. I chose Brighton as I’ve lived rather locally my whole life, and I’m enjoying being able to study whilst also still getting to live at home.

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Pharmacist committed to providing opportunities for the next generation

Pharmacy graduate Shirin Alwash shares the importance of supporting new pharmacists and the positive impact of diversity at Brighton.

Shirin, who works as a Training and Development Manager for Paydens Pharmacies, is inspiring the next generation of pharmacists.

Reflecting on her own journey and experience to create work-based training programmes to help prepare and upskill new graduates for a career in the pharmacy industry; Shirin is a true example of the Brighton Effect. She is taking that energy and using it to help others embarking on a similar career path.

Shirin also tells us about how meeting people from different backgrounds during her time at Brighton was important for the communication and relationship-building skills she has carried with her into her career.

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David Webb with Debra Humphris and Summer

Pharmacists will play an increasing role in front-line clinical healthcare, Chief Pharmaceutical Officer tells pharmacy students at Brighton

The Chief Pharmaceutical Officer for England, David Webb, on his visit to the university, told students that this was an exciting moment for the profession.

In a speech to staff and students at the University of Brighton this week, David Webb said that changes such as the introduction of prescribing skills training to the undergraduate MPharm degree and the Pharmacy First initiative will mean that pharmacists play an increasingly important role in primary healthcare delivery.

David Webb told the audience: “From 2026, all newly-qualified pharmacists will be independent prescribers. The aim is to enable better patient care and use of skill mix in pharmacy and enable effective deployment of the skills and knowledge of Pharmacists and pharmacy technicians. This is an exciting step towards opening new horizons, across all sectors, including urgent care.”

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