Differing stages of life from caterpillar to cocoon to butterfly

From caterpillar to butterfly: Brighton scientists unlock nature’s greatest transformation

Have you ever wondered how a caterpillar becomes a butterfly? It’s one of nature’s most magical transformations, and now, thanks to pioneering research at the University of Brighton, we understand it better than ever before.

In a groundbreaking study, our scientists have decoded the genetic choreography behind metamorphosis, revealing how a caterpillar doesn’t just change shape, it rewrites its entire biological blueprint. This research, led by Professor Rameen Shakur and Dr. Andrew Hesketh at the Brighton Integrative Genomics Unit, used cutting-edge DNA and RNA sequencing to track how genes are switched on and off during each stage of the transformation.

“The caterpillar doesn’t just change shape – it completely rewrites its genome,” said Professor Shakur. “That’s a profound lesson in adaptation and survival.”

Read more about this groundbreaking research on the University of Brighton webiste.

Why this matters for future biologists

This isn’t just a cool science story, it’s a glimpse into the kind of real-world, impactful research you could be part of as a Biological Sciences student at Brighton. Whether you’re fascinated by genetics, conservation, or developmental biology, this study touches on it all:

  • Genomics & molecular biology: learn how organisms regulate gene expression and adapt at the molecular level.
  • Conservation science: discover how genetic insights can help protect declining butterfly populations—key pollinators in our ecosystems.
  • Regenerative medicine: explore how nature’s ability to reprogram itself could inspire future therapies for human healing and growth.

Study where discovery happens

At Brighton, you won’t just learn about science, you’ll do science. As a student, you’ll have access to state-of-the-art facilities, and work alongside researchers who are pushing the boundaries of what we know about life itself.

Whether you’re considering an undergraduate degree or a research-focused MRes in Biological Sciences, Brighton offers a vibrant, hands-on learning environment where your curiosity can thrive.

Ready to explore the science of life?

Find out more about studying Biological Sciences at the University of Brighton.

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