Daily Dose

DOAC contra-indications

DOACs (apixaban, edoxaban, dabigatrin, rivaroxaban) are contraindicated in antiphospholipid syndrome and in patients with prosthetic heart valves. For these patients warfarin is the oral anticoagulant of choice. https://bnf.nice.org.uk/drug/rivaroxaban.html#contraIndications...
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Daily Dose

Treatment of Alzheimer’s disease

Mild-to-moderate Alzheimer’s disease: first-line options for monotherapy are donepezil, galantamine, or rivastigmine (acetylcholinesterase inhibitors)  Moderate Alzheimer’s: If acetylcholinesterase inhibitors are not tolerated or contra-indicated, memantine is a suitable alternative  Severe...
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