Clinical trial of infection-detecting bandages begins

A clinical trial of a smart bandage which changes colour when it detects infections is beginning using samples from burns patients from four UK hospitals.

The samples will undergo tests by scientists in the School of Pharmacy and Biomolecular Sciences who will look at the activation of key genes in infection-causing bacteria to evaluate the bandages’ performance

The technology, developed at the University of Bath, has potential to detect infection earlier, allowing improved treatment for burns patients as well as reducing the use of antibiotics, helping combat the threat of drug-resistant bacteria.

The trial, at Southmead Hospital Bristol, Bristol Royal Hospital for Children, Chelsea and Westminster Hospital and Queen Victoria Hospital East Grinstead, will use swabs and dressings taken from hundreds of patients to conduct tests to understand wound infection and dressing activation in laboratories in University of Brighton and Bath.

Dr Brian Jones, who is based in our school, and colleagues are leading on work to understand how well the dressing will respond to the bacteria causing these infections, and optimise this.

Dr Jones, Reader in Molecular and Medical Microbiology, said: “The dressing technology we are helping to develop here could be of real benefit to many patients. This could not only help clinicians provide the best possible treatment for patients with burns, but could also help us understand how wound infections begin and how they affect the normal healing process.” Continue reading